Histone Deacetylase 1 (HDAC1) Antibody
Product Sizes
100 ug
£671.00
3065-MSM1-P1-100UG
About this Product
- SKU:
- 3065-MSM1-P1
- Additional Names:
- Protein deacetylase HDAC1 | Protein decrotonylase HDAC1
- Application:
- ELISA, Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-HDAC1-1B7
- Clonality:
- Monoclonal
- Extra Details:
- In the intact cell; DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely; the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases; including GCN5; PCAF (for p300/ CBP-associated factor); p300/CBP and the TFIID subunit TAFII p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3); both of which are related to the yeast transcriptional regulator Rpd3p; have been identified as histone deacetylases.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human HDAC1 protein
- Isotype:
- IgG
- Molecular Weight:
- 60kDa
- Research Area:
- Infectious Disease; Nuclear Marker; Ovarian Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115380
