Recombinant Hemoglobin alpha (2 chain) Antibody
Product Sizes
100 ug
£671.00
3039-MSM3-P1ABX-100UG
About this Product
- SKU:
- 3039-MSM3-P1ABX
- Additional Names:
- Alpha-globin | Hemoglobin alpha chain
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rHBA/9167
- Clonality:
- Monoclonal
- Extra Details:
- Hemoglobin (Hgb) is coupled to four iron-binding; methene-linked tetrapyrrole rings (heme). The α (16p13.3; 5'-Î �-pseudoÎ �-pseudoα2-pseudoα1-α2-α1- Î �1-3') and β (11p15.5) globin loci determine the basic Hgb structure. The globin portion of Hgb consists of two α chains and two β chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between α and β chains are weaker than between similar globin chains; thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the α1-β2 cleavage plane. When the two α1-β2 interfaces are closely bound; Hgb has a low affinity for oxygen. Hb A; which contains two α chains plus two β chains; comprises 97% of total circulating hemoglobin. The remaining 3% of total circulating hemoglobin is comprised of Hb A-2; which consists of two α chains plus two d chains; and fetal hemoglobin (Hb F); which consists of two α chains together with two g chains.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-100) of human HBA2 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 16kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133451
