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Antibodies

Annexin A1 / (Hairy Cell Leukemia Marker) Antibody

Product Sizes
20 ug
£364.00
301-MSM6-P0-20UG
About this Product
SKU:
301-MSM6-P0
Additional Names:
Annexin I | Annexin-1 | Calpactin II | Calpactin-2 | Chromobindin-9 | Lipocortin I | Phospholipase A2 inhibitory protein | p35
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
ANXA1/3566
Clonality:
Monoclonal
Extra Details:
The ANXA1 gene belongs to the annexin family; and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL); and its protein expression is specific for HCL. Detection of ANXA1 provides a simple; highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells; suggesting it is involved in tumor suppressive and protective activities; and also is associated with treatment resistance.
Host:
Mouse
Immunogen:
Recombinant full-length human Annexin A1 protein
Isotype:
IgG2a
Molecular Weight:
38kDa
Research Area:
Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Immunology; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody