Annexin A1 / (Hairy Cell Leukemia Marker) Antibody
Product Sizes
100 ug
£671.00
301-MSM5-P1ABX-100UG
About this Product
- SKU:
- 301-MSM5-P1ABX
- Additional Names:
- Annexin I | Annexin-1 | Calpactin II | Calpactin-2 | Chromobindin-9 | Lipocortin I | Phospholipase A2 inhibitory protein | p35
- Application:
- ELISA, Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- 5E4/1
- Clonality:
- Monoclonal
- Extra Details:
- The ANXA1 gene belongs to the annexin family; and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL); and its protein expression is specific for HCL. Detection of ANXA1 provides a simple; highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells; suggesting it is involved in tumor suppressive and protective activities; and also is associated with treatment resistance.
- Host:
- Mouse
- Immunogen:
- Mixture of native proteins from human bone tissues
- Isotype:
- IgG1
- Molecular Weight:
- 35kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115352
