Recombinant Histone H1 (Pan Nuclear Marker) Antibody
Product Sizes
100 ug
£671.00
3005-MSM8-P1ABX-100UG
About this Product
- SKU:
- 3005-MSM8-P1ABX
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rAE-4
- Clonality:
- Monoclonal
- Extra Details:
- Please note that this antibody is a recombinant Mouse version of original anti-histone H1 antibody (Clone AE-4). Because the variable heavy (VH) and variable light (VL) domains are the same; recombinant antibody has the same exact reactivity as the original AE-4 MAb. There are several advantages of producing a recombinant version of a monoclonal antibody. For example; a recombinant antibody is a purer preparation of active immunoglobulin with no contaminating non-functional intact Ig or free light/heavy chains. Secondly; antibody can always be produced; even if hybridoma line is lost. Moreover; it adds the flexibility of converting the antibody to any species; isotype or format.Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A; H2B; H3; and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers; forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1; derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. This antibody is extensively used as a pan-nuclear marker.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human Histone H1 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 30kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115297
