Granzyme B (NK/T-Cell Lymphoma Marker) Antibody
Product Sizes
0.5 ml at 100ug/ml
£671.00
3002-MSM4-B1-0.5MLAT100UG
About this Product
- SKU:
- 3002-MSM4-B1
- Additional Names:
- C11 | CTLA-1 | Cathepsin G-like 1 | Cytotoxic T-lymphocyte proteinase 2 | Fragmentin-2 | Granzyme-2 | Human lymphocyte protein | SECT | T-cell serine protease 1-3E
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- GZMB/3014
- Clonality:
- Monoclonal
- Extra Details:
- Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize; bind; and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens; usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human GZMB protein (around aa 73-187) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 29-32kDa
- Research Area:
- Apoptosis; Autophagy; Cardiovascular; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=140633
