Recombinant Beta-Parvin Antibody
Product Sizes
100 ug
£671.00
29780-RBM3-P1-100UG
About this Product
- SKU:
- 29780-RBM3-P1
- Additional Names:
- Affixin
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PARVB/8214R
- Clonality:
- Monoclonal
- Extra Details:
- Beta-parvin; also known as affixin; is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin; Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells; and that its expression may influence the progression of breast cancer (Johnstone; 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan; 2007).
- Host:
- Rabbit
- Immunogen:
- N-terminal region (residues 1-91) of human b-parvin
- Isotype:
- IgG
- Molecular Weight:
- 41kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=130611
