GTF2H2 / BTF2 / TFIIH Basal Transcription Factor Antibody
Product Sizes
20 ug
£364.00
2966-MSM1-P0-20UG
About this Product
- SKU:
- 2966-MSM1-P0
- Additional Names:
- Basic transcription factor 2 44 kDa subunit | General transcription factor IIH polypeptide 2 | TFIIH basal transcription factor complex p44 subunit
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-GTF2H2-1B9
- Clonality:
- Monoclonal
- Extra Details:
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II; as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors; including TFIIA; TFIIB; TFIIE; TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits; designated p89 (XPB or ERCC3); p62; p52; p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7; cyclin H and Mat1. Both p89 and p80 have ATP-dependent helicase activity. The p62; p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human GTF2H2 protein
- Isotype:
- IgG1
- Molecular Weight:
- 44kDa
- Research Area:
- Infectious Disease; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115206
