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Antibodies

GTF2B/ TFIIB (Transcription Factor 2B) Antibody

Product Sizes
100 ug
£671.00
2959-MSM1-P1-100UG
About this Product
SKU:
2959-MSM1-P1
Additional Names:
General transcription factor TFIIB | S300-II
Application:
ELISA, Flow Cytometry
translate.label.attr.clone:
PCRP-GTF2B-1D1
Clonality:
Monoclonal
Extra Details:
In eukaryotic systems; initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes; including TFIIA; TFIIB; TFIID; TFIIE; TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Template commitment is established by the initial binding of TFIID to the TATA element of the promotor; a step which may be facilitated by TFIIA. TFIIB then acts as the bridge between TFIID and RNA polymerase II.
Host:
Mouse
Immunogen:
Recombinant full-length human GTF2Bprotein
Isotype:
IgG2b
Molecular Weight:
34.8kDa
Research Area:
Infectious Disease; Nuclear Marker; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody