PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody
Product Sizes
100 ug
£671.00
29126-MSM6-P1ABX-100UG
About this Product
- SKU:
- 29126-MSM6-P1ABX
- Additional Names:
- B7 homolog 1
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PDL1/2746
- Clonality:
- Monoclonal
- Extra Details:
- PD-L1 is a checkpoint regulator in immune cells; it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 39-191) of human CD274 (PD-L1) protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 37-50kDa
- Research Area:
- Immuno Oncology; Immunology; Mast Cell Marker; PD-1 blockade immunotherapy; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115117
