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Antibodies

PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody

Product Sizes
100 ug
£671.00
29126-MSM2-P1ABX-100UG
About this Product
SKU:
29126-MSM2-P1ABX
Additional Names:
B7 homolog 1
Application:
ELISA
translate.label.attr.clone:
PDL1/2742
Clonality:
Monoclonal
Extra Details:
PD-L1 is a checkpoint regulator in immune cells; it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Host:
Mouse
Immunogen:
Recombinant fragment of human CD274 protein (around aa 39-191) (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
37-50kDa
Research Area:
Immunology; Mast Cell Marker; PD-1 blockade immunotherapy; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody