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Antibodies

Blood Group Antigen A (CD173) Antibody

Product Sizes
100 ug
£671.00
28-MSM8-P1BX-100UG
About this Product
SKU:
28-MSM8-P1BX
Additional Names:
Fucosylglycoprotein 3-alpha-galactosyltransferase | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase | Histo-blood group A transferase | Histo-blood group B transferase | NAGAT
Application:
Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
HE-10
Clonality:
Monoclonal
Extra Details:
This MAb preferably reacts with determinants of chain A and H type 3(Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R); but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This MAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A; B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type; and are detected on erythrocytes; certain epithelial cells; and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens; including A; B; H; Lewis A; Lewis B; Lewis X; Lewis Y; and precursor type 1 chain antigens.
Host:
Mouse
Immunogen:
Mixture of erythrocytes of blood group Aand glyco protein fraction isolated from the saliva of secretors with blood group A
Isotype:
IgM
Molecular Weight:
Multiple
Research Area:
Cardiovascular
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody