Blood Group Antigen H Type 2 (CD173) Antibody
Product Sizes
200 ug
£671.00
28-MSM2-P2-200UG
About this Product
- SKU:
- 28-MSM2-P2
- Additional Names:
- Fucosylglycoprotein 3-alpha-galactosyltransferase | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase | Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase | Histo-blood group A transferase | Histo-blood group B transferase | NAGAT
- Application:
- Immunofluorescence
- translate.label.attr.clone:
- A46-B/B10
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes the blood group H type 2 antigens; trisaccharide Fuc伪1-2Gal尾1-4GlcNAc尾1 of human origin. The specificity of this MAb has been identified by haemagglutination tests; immunohistochemistry; binding inhibition studies; and absorption experiments performed with synthetic oligosaccharides. The antibody is virtually nonreactive with H type 1 antigen or with closely related type 2 structures (e.g.; Y antigen). A46-B/B10 strongly agglutinates human erythrocytes according to the amount of H substance expressed and can; therefore; easily discriminate between blood groups A1 and A2 as well as A1B and A2B (A1 and A1B are not or only weakly agglutinated). In immunohistochemistry; this antibody seems to provide a highly specific reagent for a restricted number of carcinomas and epithelial lineages in tissue sections and in vitro. This was tested on 753 blood samples. It strongly agglutinates human erythrocytes of blood groups 0; A2 and A2B; but not or only very weakly A1 and A1B. This MAb promises to be useful in the determination of A and AB subgroups in blood group serology. This MAb might also be able to define B subgroups. Among 263 B blood samples; 45 (17.1%) were negative or only weakly positive with A46-B/B10.
- Host:
- Mouse
- Immunogen:
- Human breast cancer MCF-7 cells
- Isotype:
- IgM
- Molecular Weight:
- Multiple
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114991
