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Antibodies

Recombinant Glutamine Synthetase / GLUL Antibody

Product Sizes
100 ug
£671.00
2752-MSM22-P1ABX-100UG
About this Product
SKU:
2752-MSM22-P1ABX
Additional Names:
Glutamate | ammonia ligase | Palmitoyltransferase GLUL
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
rGLUL/8620
Clonality:
Monoclonal
Extra Details:
Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes; which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers; indicating a potential role for glutamine synthetase in hepatocyte transformation.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 1-200) of human GLUL protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
42kDa
Research Area:
Cardiovascular; Mitochondria Marker; Neuroinflammation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody