TOX3 / TNRC9 Antibody
Product Sizes
100 ug
£671.00
27324-MSM1-P1ABX-100UG
About this Product
- SKU:
- 27324-MSM1-P1ABX
- Additional Names:
- CAG trinucleotide repeat-containing gene F9 protein | Trinucleotide repeat-containing gene 9 protein
- Application:
- ELISA, Western Blot
- translate.label.attr.clone:
- TOX3/1123
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a 63kDa protein; which is identified as TOX3. It contains a high mobility group (HMG)-box; which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1; a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human TOX3 protein (around aa 251-389) (Exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 63kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114906
