GCLM (DNA Mismatch Repair Protein) Antibody
Product Sizes
100 ug
£671.00
2730-MSM3-P1-100UG
About this Product
- SKU:
- 2730-MSM3-P1
- Additional Names:
- GCS light chain | Gamma-ECS regulatory subunit | Gamma-glutamylcysteine synthetase regulatory subunit | Glutamate | cysteine ligase modifier subunit
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- GCLM/4069
- Clonality:
- Monoclonal
- Extra Details:
- g-glutamylcysteine synthetase (g-GCS) is the rate limiting enzyme for glutathione (L-g-glutamyl-L-cysteinylglycine; GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. g-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation; phenolic antioxidants; heat shock; oxidants and cytokines. The human g-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human g-GCS gene encoding the regulatory subunit maps to chromosome 1p22.1. The two subunits of g-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human GCLM protein
- Isotype:
- IgG2a
- Molecular Weight:
- 31kDa
- Research Area:
- Cardiovascular; Infectious Disease; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133418
