GC Vitamin D Binding Protein Antibody
Product Sizes
100 ug
£671.00
2638-MSM2-P1-100UG
About this Product
- SKU:
- 2638-MSM2-P1
- Additional Names:
- Gc protein-derived macrophage activating factor | Gc-globulin | Group-specific component | Vitamin D-binding protein-macrophage activating factor
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- VDBP/4482
- Clonality:
- Monoclonal
- Extra Details:
- Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition; DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 35-175) of human GC protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 53kDa.
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114725
