GATA4 Antibody
Product Sizes
100 ug
£671.00
2626-MSM1-P1-100UG
About this Product
- SKU:
- 2626-MSM1-P1
- Additional Names:
- GATA-binding factor 4
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- PCRP-GATA4-1A7
- Clonality:
- Monoclonal
- Extra Details:
- Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver; HeLa and endothelial cells; as well as erythroid cells. Studies with a modified GATA consensus sequence; AGATCTTA; have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4; GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart; pancreas and ovary; lung and liver tissues exhibit GATA-6; but not GATA-4; expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap; it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa262-321) of human GATA4 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 44.57kDa
- Research Area:
- Cardiac Stem Cells; Cardiovascular; Developmental Biology; Mesenchymal Stem Cell Differentiation; Nuclear Marker; Stem Cell Differentiation; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133282
