Recombinant GATA-3 (Breast and Urothelial Marker) Antibody
Product Sizes
100 ug
£671.00
2625-RBM16-P1-100UG
About this Product
- SKU:
- 2625-RBM16-P1
- Additional Names:
- GATA-binding factor 3
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- GATA3/7686R
- Clonality:
- Monoclonal
- Extra Details:
- GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues; including hematopoietic cells; skin; kidney; mammary gland; and the central nervous system. Among several other roles; GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas; but none of prostate or renal carcinomas.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa150-250) of human GATA-3 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 50kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133281
