SERBP1 / PAI-RBP1 Antibody
Product Sizes
100 ug
£671.00
26135-MSM8-P1ABX-100UG
About this Product
- SKU:
- 26135-MSM8-P1ABX
- Additional Names:
- PAI1 RNA-binding protein 1 | SERPINE1 mRNA-binding protein 1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- SERBP1/3498
- Clonality:
- Monoclonal
- Extra Details:
- SERBP1 is a membrane-associated protein that localizes to the nucleus; the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability; as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition; SERBP1 interacts with Mi2-伪 and may be involved in chromatin remodeling. It also interacts with PGRMC1 and participates in the transduction of Progesterone s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer; suggesting a possible role in tumorigenesis and tumor metastasis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 60kDa
- Research Area:
- Ovarian Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114662
