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Antibodies

CCR4-NOT transcription complex; subunit 10 (CNOT10) Antibody

Product Sizes
20 ug
£364.00
25904-MSM1-P0-20UG
About this Product
SKU:
25904-MSM1-P0
Application:
ELISA, Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
PCRP-CNOT10-1D5
Clonality:
Monoclonal
Extra Details:
CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved; multi-component complex known to be involved in transcription; as well as in mRNA degradation. Various subunits (e.g. CNOT1; CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect; this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.
Host:
Mouse
Immunogen:
Recombinant full-length human CNOT10 protein
Isotype:
IgG2c
Molecular Weight:
82.31kDa
Research Area:
Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody