Ku (p70/p80) (Nuclear Marker) Antibody
Product Sizes
0.5 ml at 100ug/ml
£671.00
2547-MSM1-PE-100T-0.5MLAT100UG
About this Product
- SKU:
- 2547-MSM1-PE-100T
- Additional Names:
- 5'-deoxyribose-5-phosphate lyase Ku70 | 70 kDa subunit of Ku antigen | ATP-dependent DNA helicase 2 subunit 1 | ATP-dependent DNA helicase II 70 kDa subunit | CTC box-binding factor 75 kDa subunit | DNA repair protein XRCC6 | Lupus Ku autoantigen protein p70 | Thyroid-lupus autoantigen | X-ray repair complementing defective repair in Chinese hamster cells 6
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- KU729
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a dimer of two proteins of 70kDa and ~80kDa; identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer; which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling; proliferation; DNA repair; replication; transcriptional activation; and apoptosis.
- Host:
- Mouse
- Immunogen:
- Nuclear extract of human HL-60 cells
- Isotype:
- IgG1
- Molecular Weight:
- 70kDa & 80kDa
- Research Area:
- Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=140363
