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Antibodies

Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker) Antibody

Product Sizes
20 ug
£364.00
250-MSM2-P0-20UG
About this Product
SKU:
250-MSM2-P0
Additional Names:
Alkaline phosphatase Regan isozyme | Placental alkaline phosphatase 1
Application:
ELISA
translate.label.attr.clone:
ALPP/238
Clonality:
Monoclonal
Extra Details:
PLAP is a tissue specific; trophoblast-derived; 70kDa; glycosyl-phosphatidylinositol (GPI)-anchored; dimeric; Zn2+ metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans; PLAP; germ cell AP (GCAP) and intestinal AP; are 90-98% homologous. Non-tissue specific AP is found in kidney; liver and bone. This MAb binds equally well to all common allelic variants (S; F; FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S; F; FS and I phenotypes.
Host:
Mouse
Immunogen:
Recombinant full-length human ALPP protein
Isotype:
IgG2a
Molecular Weight:
70kDa
Research Area:
Mesenchymal Stem Cell Differentiation; Stem Cell Differentiation
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody