Placental Alkaline Phosphatase (PLAP) (Germ Cell Tumor Marker) Antibody
Product Sizes
100 ug
£671.00
250-MSM1X-P1-100UG
About this Product
- SKU:
- 250-MSM1X-P1
- Additional Names:
- Alkaline phosphatase Regan isozyme | Placental alkaline phosphatase 1
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM593
- Clonality:
- Monoclonal
- Extra Details:
- Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast; gastrointestinal; prostatic; and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive; but they regularly fail to stain with anti-EMA; whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human ALPP protein
- Isotype:
- IgG2b
- Molecular Weight:
- 70kDa
- Research Area:
- Mesenchymal Stem Cell Differentiation; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114424
