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Antibodies

Alkaline Phosphatase (Tissue-Nonspecific) Antibody

Product Sizes
100 ug
£671.00
249-MSM1-P1-100UG
About this Product
SKU:
249-MSM1-P1
Additional Names:
Alkaline phosphatase liver/bone/kidney isozyme | Phosphoamidase | Phosphocreatine phosphatase
Application:
Immunohistochemistry
translate.label.attr.clone:
ALPL/597
Clonality:
Monoclonal
Extra Details:
There are at least four distinct but related alkaline phosphatases: intestinal; placental; placental-like; and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2; while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is; therefore; referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however; mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia; a disorder that is characterized by hypercalcemia and includes skeletal defects.
Host:
Mouse
Immunogen:
Recombinant human ALPL protein
Isotype:
IgG1
Molecular Weight:
55kDa
Research Area:
Cardiovascular
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody