Recombinant Glucagon (Marker of Glucagonoma) Antibody
Product Sizes
20 ug
£364.00
2461-RBM4-P0-20UG
About this Product
- SKU:
- 2461-RBM4-P0
- Additional Names:
- Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM; OXY); Glucagon; Glucagon-like peptide 1 (GLP-1); Alternative names: Incretin hormone Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- GCG/13090R
- Clonality:
- Monoclonal
- Extra Details:
- Glucagon is a pancreatic hormone that functions as an antagonist to Insulin; stimulating the conversion of glycogen to glucose and increasing blood sugar levels. Glucagon-like peptide-1 (GLP-1); Glucagon-like peptide-2 (GLP-2); VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the Glucagon family of hormones. GLP-1 functions as a transmitter in the central nervous system; inhibiting feeding and drinking behavior; whereas GLP-2 is a stimulator of intestinal epithelial growth. VIP causes vasodilation resulting in the lowering of blood pressure. PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones; including growth hormone. Glucagon antibody detects glucagon-secreting cells and tumors such as glucagonomas; of which approximately 80% are malignant.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa1-100) of human GCG protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 19kDa (Proglucagon); 3kDa (Glucagon)
- Research Area:
- Digestion; Endocrine; Gastrointestinal Tract; Lipid Metabolism; Metabolism
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=143484
