Recombinant SLC7A11 / xCT Antibody
Product Sizes
100 ug
£671.00
23657-RBM3-P1ABX-100UG
About this Product
- SKU:
- 23657-RBM3-P1ABX
- Additional Names:
- Amino acid transport system xc | -Calcium channel blocker resistance protein CCBR1 | Solute carrier family 7 member 11 | xCT
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- SLC7A11/9136R
- Clonality:
- Monoclonal
- Extra Details:
- xCT; also known as SLC7A11 (solute carrier family 7; (cationic amino acid transporter; y+ system) member 11) or CCBR1; is a 501 amino acid multi-pass membrane protein that belongs to the polyamine-organocation superfamily of amino acid transporters. Existing as a disulfide-linked heterodimer with CD98; xCT functions as a member of a heteromeric Na+-independent anionic amino acid transport system that specifically facilitates the exchange of anionic amino acids for anionic forms of cystine and glutamate; thereby mediating the formation of glutathione within the cell. Due to its involvement in amino acid transport; xCT is associated with the pathogenesis of gliomainduced neurodegeneration and brain edema; as well as pancreatic cancer. The gene encoding xCT maps to human chromosome 4; which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragments of human SLC7A11 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 40kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=135978
