Recombinant TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody

Product Sizes

100 ug

£671.00

23650-RBM7-P1-100UG

About this Product

SKU:: 23650-RBM7-P1
Additional Names:: Ataxia telangiectasia group D-associated protein
Application:: Immunohistochemistry
translate.label.attr.clone:: TRIM29/9257R
Clonality:: Monoclonal
Extra Details:: It recognizes a 66kDa protein; which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin; a substrate for the PKC family of protein kinases; and with hPKCI-1; an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs; suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer; and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy; when used in a panel with TTF-1; p63; CK5/6; and Napsin-A antibodies.
Host:: Rabbit
Immunogen:: Recombinant fragment (around aa 1-200) of human TRIM29 protein (exact sequence is proprietary)
Isotype:: IgG
Molecular Weight:: 66kDa
Research Area:: Cytokine Signaling; Immunology
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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