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Antibodies

Sirtuin 3 (SIRT3) Antibody

Product Sizes
20 ug
£364.00
23410-MSM1-P0-20UG
About this Product
SKU:
23410-MSM1-P0
Additional Names:
Regulatory protein SIR2 homolog 3 | SIR2-like protein 3
Application:
ELISA, Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
PCRP-SIRT3-1C10
Clonality:
Monoclonal
Extra Details:
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers; but they can also form heterodimers with each other. However; this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
Host:
Mouse
Immunogen:
Recombinant full-length human SIRT3 protein
Isotype:
IgG2a
Molecular Weight:
43.57kDa
Research Area:
Cardiovascular; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody