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Antibodies

Fibronectin Antibody

Product Sizes
20 ug
£364.00
2335-MSM7-P0-20UG
About this Product
SKU:
2335-MSM7-P0
Additional Names:
Cold-insoluble globulin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
translate.label.attr.clone:
Fn-3
Clonality:
Monoclonal
Extra Details:
Fibronectins are disulfide-linked; dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen; glycosaminoglycans; transglutaminase; and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion; tissue organization; and wound healing. Fibronectins are present in basement membranes; interstitial connective tissue matrix; and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin; but not plasma fibronectin.
Host:
Mouse
Immunogen:
FR5 cells; derived by SV40 transformation of human mammary epithelial cells.
Isotype:
IgG1
Molecular Weight:
220kDa (monomer); 440kDa (dimer)
Research Area:
Articular Cartilage Extracellular Matrix; Cardiovascular; Cytokine Signaling; Immunology; Infectious Disease; Lung Cancer; Mesenchymal Stem Cell Differentiation; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody