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Antibodies

Flt3 / CD135 (Marker of Acute Myeloid Leukemia) Antibody

Product Sizes
100 ug
£671.00
2322-MSM7-P1-100UG
About this Product
SKU:
2322-MSM7-P1
Additional Names:
FL cytokine receptor | Fetal liver kinase-2 | Fms-like tyrosine kinase 3 | Stem cell tyrosine kinase 1
Application:
Immunohistochemistry
translate.label.attr.clone:
FLT3/9887
Clonality:
Monoclonal
Extra Details:
Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor); Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells; a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1; designated Flt-3/Flk-2; is expressed at high levels in hematopoietic cells and also in neural; gonadal; hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa500-800) of human FLT3 protein (exact sequence is proprietary)
Isotype:
IgG2
Molecular Weight:
160kDa
Research Area:
AKT Signaling; Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology; Infectious Disease; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody