Recombinant Filaggrin (Keratinocyte Differentiation Marker) Antibody
Product Sizes
100 ug
£671.00
2312-RBM8-P1-100UG
About this Product
- SKU:
- 2312-RBM8-P1
- Application:
- Western Blot
- translate.label.attr.clone:
- FLG/3909R
- Clonality:
- Monoclonal
- Extra Details:
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor; profilaggrin (consisting of multiple filaggrin units of 324 aa each); which is localized in keratohyalin granules; and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer; suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
- Host:
- Rabbit
- Immunogen:
- Recombinant human Filaggrin protein fragment (around aa 198-288) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 26-45kDa (Processed); 350kDa (Profilaggrin)
- Research Area:
- Developmental Biology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=114007
