FOXI1 / Forkhead Box I1 (Transcription Factor) Antibody
Product Sizes
100 ug
£671.00
2299-MSM1-P1ABX-100UG
About this Product
- SKU:
- 2299-MSM1-P1ABX
- Additional Names:
- Forkhead-related protein FKHL10 | Forkhead-related transcription factor 6 | Hepatocyte nuclear factor 3 forkhead homolog 3
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PCRP-FOXI1-1C4
- Clonality:
- Monoclonal
- Extra Details:
- FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice; the formation of Peyer's patches is affected; particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa104-258) of human FOXL1 protein (exact sequence is proprietary)
- Isotype:
- IgG2a
- Molecular Weight:
- 36-41kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133247
