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Antibodies

Recombinant D-Dimer / Fibrinogen gamma chain Antibody

Product Sizes
100 ug
£671.00
2266-RBM3-P1-100UG
About this Product
SKU:
2266-RBM3-P1
Additional Names:
Human FGG antibody Fibrinogen gamma chain antibody; Fibrinogen gamma polypeptide antibody; fibrinogen gamma-b chain antibody
Application:
Western Blot
translate.label.attr.clone:
FGG/13043R
Clonality:
Monoclonal
Extra Details:
The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: a; b and g. Fibrinogen is important in platelet aggregation; the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X; IX; V and VIII); which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury; Fibrinogen is cleaved by Thrombin to form Fibrin; which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading; display vasoconstrictor and chemotactic activities and are mitogens for several cell types. This antibody is directed against a neoantigenic determinant expressed on the human fragment D-dimer. D-dimer is a protein fragment (small piece) that's made when a blood clot dissolves in your body. At D-dimer test is done to determine if a person has any blood clotting disorder.
Host:
Rabbit
Immunogen:
Recombinant human FGA protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
57kDa
Research Area:
Cardiovascular
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody