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Antibodies

Fibrinogen Alpha Chain Antibody

Product Sizes
100 ug
£671.00
2243-MSM1-P1BX-100UG
About this Product
SKU:
2243-MSM1-P1BX
Application:
ELISA, Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
UC45
Clonality:
Monoclonal
Extra Details:
The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation; the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X; IX; V and VIII); which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury; Fibrinogen is cleaved by Thrombin to form Fibrin; which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading; display vasoconstrictor and chemotactic activities; and are mitogens for several cell types.
Host:
Mouse
Immunogen:
Human acute monoblastic leukemia cells.
Isotype:
IgM
Molecular Weight:
30kDa
Research Area:
Cardiovascular; Complement System; Immunology; Infectious Disease; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody