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Antibodies

FCGRT / FcRn (IgG Transporter) Antibody

Product Sizes
100 ug
£671.00
2217-MSM2-P1-100UG
About this Product
SKU:
2217-MSM2-P1
Additional Names:
IgG Fc fragment receptor transporter alpha chain | Neonatal Fc receptor
Application:
Immunohistochemistry
translate.label.attr.clone:
FCGRT/2932
Clonality:
Monoclonal
Extra Details:
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk; thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface; thus protecting IgG from lysosomal degradation.
Host:
Mouse
Immunogen:
Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
46kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody