Coagulation Factor VII / F7 Antibody
Product Sizes
100 ug
£671.00
2155-MSM2-P1-100UG
About this Product
- SKU:
- 2155-MSM2-P1
- Additional Names:
- Proconvertin | Serum prothrombin conversion accelerator
- Application:
- ELISA, Immunohistochemistry
- translate.label.attr.clone:
- F7/3512
- Clonality:
- Monoclonal
- Extra Details:
- Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X; IX; V and VIII); which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator; proconvertin; F7; Factor VII) is a 406 amino acid; vitamin K-dependent; single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A; Factor X A; Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A; an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain; containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized; with hemorrhagic diathesis occurring at extremely low levels.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 366-466) of human F7 protein
- Isotype:
- IgG2
- Molecular Weight:
- 200/80/73/50/43kDa
- Research Area:
- Cardiovascular; Mitochondria Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133152
