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Antibodies

CD142 / Coagulation factor III; tissue factor / F3 Antibody

Product Sizes
20 ug
£364.00
2152-MSM2-P0-20UG
About this Product
SKU:
2152-MSM2-P0
Additional Names:
CD142 antibody; CD142 antigen antibody; Coagulation factor III (thromboplastin tissue factor) antibody; Coagulation factor III antibody; F3 antibody; FLJ17960 antibody; TF antibody; TF_HUMAN antibody; TFA antibody; Thromboplastin antibody; Tissue factor antibody
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
CD142/9196
Clonality:
Monoclonal
Extra Details:
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X; IX; V and VIII); which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V; FV; proaccelerin; labile factor) is a 2;196 amino acid; single chain glycoprotein that is cleaved by Thrombin to yield an active; Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells; Factor Va coordinates into a prothrombinase complex; which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF); also designated coagulation Factor III) is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa50-250) of human F3 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
47kDa
Research Area:
Colon Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody