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Antibodies

ETS2 (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
2114-MSM1-P1ABX-100UG
About this Product
SKU:
2114-MSM1-P1ABX
Application:
ELISA, Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-ETS2-1D9
Clonality:
Monoclonal
Extra Details:
ETS2 (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice; a mutation that is associated with widespread disruption of laminated regions of the brain; leading to impaired motor coordination; tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1; in a signaling pathway that controls cell positioning in the developing brain; and is also thought to be a direct effector of the neurotrophin BDNF.
Host:
Mouse
Immunogen:
Recombinant full-length human ETS2 protein
Isotype:
IgG2b
Molecular Weight:
52kDa
Research Area:
Cardiovascular; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody