ETS1 (Marker of Tumor Metastasis) Antibody
Product Sizes
100 ug
£671.00
2113-MSM1-P1ABX-100UG
About this Product
- SKU:
- 2113-MSM1-P1ABX
- Additional Names:
- p54
- Application:
- ELISA
- translate.label.attr.clone:
- ETS1/1801
- Clonality:
- Monoclonal
- Extra Details:
- ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases; cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells; where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting; activated and apoptotic lymphocytes.
- Host:
- Mouse
- Immunogen:
- Recombinant human ETS1 fragment (around aa137-230) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 54kDa
- Research Area:
- Angiogenesis; Cardiovascular; Endothelial Cell Marker; Hypoxia; Nuclear Marker; Ovarian Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113642
