Recombinant ER-beta1 (Estrogen Receptor beta-1) Antibody
Product Sizes
100 ug
£671.00
2100-RBM15-P1-100UG
About this Product
- SKU:
- 2100-RBM15-P1
- Additional Names:
- Nuclear receptor subfamily 3 group A member 2
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- ESR2/7006R
- Clonality:
- Monoclonal
- Extra Details:
- Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors; including ER-alpha and ER-beta; contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus; though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events; including dissociation from heat shock proteins; receptor dimerization; phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.
- Host:
- Rabbit
- Immunogen:
- C-terminus fragment of recombinant human estrogen receptor beta protein
- Isotype:
- IgG
- Molecular Weight:
- 53-59kDa
- Research Area:
- Breast Cancer; Cardiovascular; Infectious Disease; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113641
