ER-beta (Estrogen Receptor ß5) Antibody
Product Sizes
20 ug
£364.00
2100-MSM12-P0-20UG
About this Product
- SKU:
- 2100-MSM12-P0
- Additional Names:
- Nuclear receptor subfamily 3 group A member 2
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PPG5/25
- Clonality:
- Monoclonal
- Extra Details:
- This MAb specifically recognizes human estrogen receptor beta 5 (ERB5); a splice variant of the nuclear receptor hormone ER beta (ESR2); shown to exist in at least five isoforms (ERB1-ERB5). No cross-reactivity is seen with estrogen receptor beta 1 or 2 isoform. This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus; cytoplasm; and mitochondria. Upon binding to 17beta-estradiol or related ligands; the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members.
- Host:
- Mouse
- Immunogen:
- Tuberculin conjugated synthetic peptide (LLSHVRHARYAP); derived from the C-terminus of human Estrogen Receptor beta 5
- Isotype:
- IgG1
- Molecular Weight:
- 59kDa
- Research Area:
- Breast Cancer; Cardiovascular; Infectious Disease; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113614
