Recombinant Estrogen Receptor; alpha (Marker of Estrogen Dependence) Antibody
Product Sizes
20 ug
£364.00
2099-MSM51-P0-20UG
About this Product
- SKU:
- 2099-MSM51-P0
- Additional Names:
- ER-alpha | Estradiol receptor | Nuclear receptor subfamily 3 group A member 1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rESR1/9525
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 67kDa; which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons; being translated into a protein with six functionally discrete domains; labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas.The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to antiestrogen (e.g. tamoxifen) therapy.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment corresponding to C-terminus of human ESR1 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- ~67kDa
- Research Area:
- Breast Cancer; Cardiovascular; Infectious Disease; Ovarian Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=143371
