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Antibodies

Estrogen Receptor; alpha (Marker of Estrogen Dependence) Antibody

Product Sizes
0.5 ml at 100ug/ml
£671.00
2099-MSM2-PE-100T-0.5MLAT100UG
About this Product
SKU:
2099-MSM2-PE-100T
Additional Names:
ER-alpha | Estradiol receptor | Nuclear receptor subfamily 3 group A member 1
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
ER506
Clonality:
Monoclonal
Extra Details:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 2-185) of human Estrogen Receptor alpha protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
~67kDa
Research Area:
Breast Cancer; Cancer; Cardiovascular; Infectious Disease; Ovarian Cancer; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody