ERCC1 / RAD10 (Tumor Progression Marker) Antibody
Product Sizes
100 ug
£671.00
2067-MSM2-P1ABX-100UG
About this Product
- SKU:
- 2067-MSM2-P1ABX
- Application:
- ELISA, Western Blot
- translate.label.attr.clone:
- ERCC1/2318
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 110kDa; identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae; which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC); squamous cell carcinoma of the head; ovarian cancer and esophageal cancer.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 110kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113467
