Emerin (Papillary Thyroid Carcinoma and EDMD Marker) Antibody
Product Sizes
100 ug
£671.00
2010-MSM2-P1-100UG
About this Product
- SKU:
- 2010-MSM2-P1
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- EMD/2168
- Clonality:
- Monoclonal
- Extra Details:
- Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD); which is characterized by slowly progressing contractures; skeletal muscle wasting and cardiomyopathy. Reportedly; lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina; and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.
- Host:
- Mouse
- Immunogen:
- Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 37kDa
- Research Area:
- Cardiovascular; Nuclear Marker; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113317
