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Antibodies

EIF4E Antibody

Product Sizes
20 ug
£364.00
1977-MSM1-P0-20UG
About this Product
SKU:
1977-MSM1-P0
Additional Names:
eIF-4F 25 kDa subunit | mRNA cap-binding protein
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
PCRP-EIF4E-1D3
Clonality:
Monoclonal
Extra Details:
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4E; eIF4A and eIF4G. Together; the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E binds to the mRNA cap during an early step in the initiation of protein synthesis. eIF4A acts as an ATP-dependent RNA helicase. eIF4G acts as a bridge between eIF4E; eIF4A and the eIF3 complex.
Host:
Mouse
Immunogen:
Recombinant full-length human EIF4E protein
Isotype:
IgG2a
Molecular Weight:
25.1kDa
Research Area:
AKT Signaling; Cytokine Signaling; Immunology; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody