EIF4A2 (Eukaryotic Initiation Factor 4A-II) Antibody
Product Sizes
100 ug
£671.00
1974-MSM1-P1-100UG
About this Product
- SKU:
- 1974-MSM1-P1
- Additional Names:
- ATP-dependent RNA helicase eIF4A-2
- Application:
- ELISA
- translate.label.attr.clone:
- PCRP-EIF4A2-2B5
- Clonality:
- Monoclonal
- Extra Details:
- Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A; eIF4E and eIF4G; binds mRNA at a5'-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B; the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5' cap; eIF4A (I; II) are bidirectional RNA helicases; and eIF4G (I; II) are scaffolding proteins which coordinate eIF4E; eIF4A; eIF3and the 40S ribosome. Human eIF4AI (eIF4A; DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human EIF4A2 protein
- Isotype:
- IgG2a
- Molecular Weight:
- 46kDa
- Research Area:
- Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113281
