Reelin Antibody
Product Sizes
100 ug
£671.00
19699-MSM1-P1ABX-100UG
About this Product
- SKU:
- 19699-MSM1-P1ABX
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- RELN/4498
- Clonality:
- Monoclonal
- Extra Details:
- Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice; a mutation that is associated with widespread disruption of laminated regions of the brain; leading to impaired motor coordination; tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1; in a signaling pathway that controls cell positioning in the developing brain; and is also thought to be a direct effector of the neurotrophin BDNF.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 1796-2115) of human RELN protein
- Isotype:
- IgG2b
- Molecular Weight:
- 387.5kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113256
