EIF2S1 / EIF-2 alpha (EIF2A) Antibody
Product Sizes
20 ug
£364.00
1965-MSM2-P0-20UG
About this Product
- SKU:
- 1965-MSM2-P0
- Additional Names:
- Eukaryotic translation initiation factor 2 subunit alpha
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-EIF2S1-1E2
- Clonality:
- Monoclonal
- Extra Details:
- The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits; designated eIF2a; eIF2band eIF2g (eukaryotic translation initiation factor 2 a; band g; respectively); all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2a; also known as EIF2S1 or EIF2; is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner); thereby initiating translation. In addition; the phosphorylation state of eIF2a controls the rate of tRNA translation. When eIF2a is not phosphorylated; translation occurs at a normal rate. However; upon phosphorylation by one of several kinases; eIF2a is stabilized; thus preventing the GDP/GTP exchange reaction and slowing translation.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human EIF2S1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 36kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=113255
